18F-Sodium fluoride (NaF) is primarily a skeletal imaging agent which can be localized in extraosseous calcified foci.
Published in 15 October 2021
The association between Parkinsonism and BS has already been reported in only three patients worldwide.
Published in 15 December 2015
Studies of radiation interactions with tissue equivalent material find importance in efforts that seek to avoid unjustifiable dose to patients, also in ensuring quality control of for instance nuclear medicine imaging equipment. Use of the Monte Carlo (MC) simulation tool in such characterization processes allows for the avoidance of costly experiments involving transmitted X- and γ-ray spectrometry.
Published in 01 April 2019
Calcium channel blockers (CCBs) are among the most widely used prescribed drugs for the treatment of cardiovascular diseases. The present study investigates the effect of verapamil, which is most commonly used as a CCB, on kidney function using radionuclide imaging.
Published in 01 January 2019
Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy with 177Lu-PSMA-617 has shown promising results in patients with metastasized castration-resistant prostate cancer.
Published in 01 February 2022
(111)In-pentetreotide [(111)In-octreoscan] is the most widely used radiolabeled somatostatin analog for evaluating neuroendocrine tumor overexpression of somatostatin receptors.
Published in 01 May 2013
Abnormalities in the mitochondria have been linked to psoriasis, a chronic immune-mediated inflammatory skin disease. The mitochondrial DNA (mtDNA) is present in thousands of copies per cell and altered mtDNA copy number (mtDNA-CN), a common indicator of mitochondrial function, has been proposed as a biomarker for several diseases including autoimmune diseases.
Published in 29 June 2022
SUV normalized by total body weight is affected by the amount of body fat. The SUV of normal tissues and lesions is higher (overestimated) in obese patients than in patients with a normal body mass index (BMI). SUL (SUV normalized by lean body mass [LBM]) is recommended for more accurate SUV results.
Published in 01 June 2020
Tc-dimercaptosuccinic acid (DMSA) scan is the current gold standard in detecting parenchymal changes, particularly scarring, in pyelonephritis. Recently, magnetic resonance imaging (MRI) is gaining popularity in the diagnosis of pyelonephritis. The aim of this study is to perform a meta-analysis on studies directly comparing MRI to DMSA scan in patients with pyelonephritis.
Published in 01 November 2020
To analyse the relationship between 18F-labelled sodium fluoride (NaF) uptake and lumbar back pain in patients with lumbosacral transitional vertebra (LSTV) a congenital malformation of the lumbosacral spine.
Published in 01 August 2020
99Mo/99mTc generators play a significant role in supplying 99mTc for diagnostic interventions in nuclear medicine. However, the applicability of using low specific activity (LSA) 99Mo asks for sorbents with high sorption capacity. Herein, this study aims to evaluate the sorption behavior of LSA 99Mo towards several CeO2 nano-sorbents developed in our laboratory.
Published in 07 May 2022
Small round cell tumors (SRCTs) are a group of malignancies (non-Hodgkin lymphoma, neuroblastoma, retinoblastoma, hepatoblastoma, nephroblastoma, rhabdomyosarcoma, small cell anaplastic carcinoma, Ewing sarcomal peripheral neuroectodermal tumor, and desmoplastic small round cell tumor), characterized both cytologically and histologically by a predominantly small round to oval, and relatively undifferentiated cells.
Published in 01 July 2004
68Ga-PSMA is an excellent radiotracer for both staging and detection of recurrence in prostate cancer, but it can also be useful in other solid tumors due to tumor-associated angiogenic factors and endothelial cell sprouting.
Published in 01 August 2021
A 64-year-old woman with metastatic breast cancer on follow-up had suspicious recurrent brain metastases. She underwent F-FDG PET/CT, F-PSMA 1007 brain PET/CT, and brain MRI.
Published in 01 February 2020
We previously reported the 68Ga-labeled prostate-specific membrane antigen (PSMA)-11 and 99mTc-dimercaptosuccinic acid (DMSA) images of the first patient in our prospective research comparing renal 68Ga-PSMA-11 PET with 99mTc-DMSA scanning in adults with pyelonephritis.
Published in 01 March 2022
To examine the role of the transcription factor nuclear factor-erythroid 2 (NF-E2)-related factor 2 (Nrf2) and the SAFE pathway (JAK/STAT) in the induction of germ cell apoptosis (GCA) and the protective role of epigallocatechin-3-gallate (EGCG) during testicular ischemia reperfusion injury (tIRI). Male Sprague-Dawley rats (n = 18) were divided into three groups: sham, unilateral tIRI, tIRI + epigallocatechin-3-gallate (EGCG, 50 mg/Kg).
Published in 01 April 2020
Nuclear pore complex (NPC) is a fundamental component of the nuclear envelope and is key to the nucleocytoplasmic transport. Mutations in several NUP genes that encode individual components of NPC known as nucleoporins have been identified in recent years among patients with static encephalopathies characterized by developmental delay and microcephaly.
Published in 01 March 2019
Comparative analyses have identified genomic regions potentially involved in human evolution but do not directly assess function. Human accelerated regions (HARs) represent conserved genomic loci with elevated divergence in humans.
Published in 06 October 2016
Thyroid scintigraphy plays an important role in the anatomical and functional evaluation of thyroid nodules which carry the risk of malignancy. The presence of multiple nodules carries overall smaller risk of cancer than solitary nodule.
Published in 01 May 2015
Mitochondrial Sequence Variation, Haplotype Diversity, and Relationships Among Dromedary Camel-Types
Dromedary camels are outstanding livestock that developed efficient abilities to tolerate desert conditions. Many dromedary camel-types (i.e., named populations) exist but lack defined specific breed standards, registries, and breeders' governing organizations.
Published in 30 August 2021