In this paper, authors try to briefly bring together current knowledge regarding apathy as a transdiagnostic construct, from conceptual insights to measurement, neurobiology, and treatment.
Published in 01 August 2022
No single neurotransmitter aberration could explain the heterogeneity of schizophrenia syndrome and thus, treatment strategies capitalizing solely on a single neurotransmitter system (e.g., DA blockade) is less likely to be fully successful on clinical grounds. Hence, there is a pressing need to develop newer antipsychotics above and beyond DA antagonism.
Published in 28 February 2023
Autism Spectrum Disorder (ASD) is a complex highly heritable disorder, in which multiple environmental factors interact with the genes to increase its risk and lead to variable clinical presentations and outcomes.
Published in 24 January 2021
ASD is commonly associated with a host of challenging behaviours. Pharmacotherapy is indicated if psycho-social and educational interventions fail. Atypical antipsychotics have the strongest evidence-base so far, with both risperidone and aripiprazole are FDA-approved.
Published in 27 October 2022
Al-Mutawa, chief psychologist at Kuwait's psychiatric hospital, focuses on three topics in his brief essay on health care ethics in his country. The first is the conflict between the Western moral framework of many aspects of health care and the religious and social traditions of an Islamic country. This conflict manifests itself in such areas as reproductive medicine, truthtelling and informed consent, and terminal care.
Published in 01 July 1989
The oil-rich member states of the Gulf Cooperation Council (GCC) attract large numbers of migrant workers. The reported rates of psychiatric morbidity among these migrant workers are higher than among nationals, while the mental health services in the GCC countries remain inadequate in terms of both staff and service delivery.
Published in 01 November 2014
Microglia are the resident immune cells of the brain, constituting the powerhouse of brain innate immunity. They originate from hematopoietic precursors that infiltrate the developing brain during different stages of embryogenesis, acquiring a phenotype characterized by the presence of dense ramifications.
Published in 19 September 2020
Mental health is a key component of health, yet appropriate care is limited. Evidence concerning child and adolescent mental health has predominantly come from western countries, while the Middle East region, with a large youth population, has reported very little on it. This original, cross-sectional study of child and adolescent psychiatry in the Middle East provides an assessment of current postgraduate programs, services and what is needed to build workforce capacity.
Published in 01 January 2020
Although mental disorders are a leading cause of disability in the Arab region, which includes 5·54% of the global population, Arab countries produce only 1·0% of the global output of peer-reviewed publications in mental health research.
Published in 01 November 2019
Non-communicable diseases (NCDs) have been on the rise in low- and middle-income countries (LMICs) over the last few decades and represent a significant healthcare concern. Over 85% of "premature" deaths worldwide due to NCDs occur in the LMICs.
Published in 27 July 2020
Alemtuzumab, a humanized anti-CD52 monoclonal antibody, has been approved as a treatment in persons with active relapsing-remitting multiple sclerosis (RRMS). Real-world data in middle east is very limited. We aimed to evaluate the effectiveness and safety of alemtuzumab in a real-world clinical setting.
Published in 01 June 2023
Sociocultural considerations and persistence of indiscriminate prescription habits for addicts may have contributed in shifting the pattern of misused drugs from traditional alcohol and illicit drugs to predominantly iatrogenic dependence on benzodiazepines. The clinical profile and the rationale for the long-adopted detoxification treatment of 120 patients were studied.
Published in 01 December 1989
A retrospective analysis of the in-patients' case notes of 55 chronic epileptics admitted for psychiatric treatment to Kuwait Psychological Medicine Hospital revealed that the commonest seizure type was generalized grand mal epilepsy.
Published in 01 March 1990
The national MS registry was established in 2010 to assess the change in epidemiological status. The last reported data of the prevalence and incidence in Kuwait was in 2013.
Published in 01 July 2019
The concept of metabolic syndrome in psychiatry provides a united front for confronting a series of metabolic changes that are predictive of cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM), which are highly prevalent in severe mental disorders (SMDs), such as schizophrenia, bipolar disorders, and severe depression.
Published in 01 April 2011
Literature on ADHD has taken long strides recently as heaps of new data are pouring in through countless papers. Here, authors try to outline changing paradigms in ADHD practice. DSM-5 changes regarding the typology and diagnostic criteria are highlighted.
Published in 28 February 2023
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disorder of the central nervous system that predominantly targets optic nerves and spinal cord. Studies of NMOSD are scarce in the Middle East.
Published in 01 September 2020
Violence against doctors has already been identified as a matter of particular concern. Both the severity and the psychological sequelae of violence are difficult to quantify.
Published in 01 June 1999
Multiple Sclerosis (MS) is a chronic neurological disease with heavy economic and social burdens resulting in significant disability.
Published in 14 May 2019
To investigate type 2 diabetes as a risk factor for COVID-19 death following hospital admission in Kuwait.
Published in 01 October 2021