Agomelatine Monotherapy for Autism-A Case Report
Affiliations
Affiliations
- Naguy, MBBCh, MSc, Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Jamal Abdul-Nassir St, Shuwaikh, State of Kuwait.
- Pridmore, MBBS, BMedSc, MD, FRANZCP, FAFPHM, FAChAM, FFPMAZCP, AM,Senior Professor of Psychiatry, University of Tasmania, Hobart, Australia.
- Jamali, MD, MSc, General Adult Psychiatrist, KCMH, Kuwait.
- Hasan, MSc (Psychol), Psychotherapist, School Psychiatry Clinic, MOE, Az-Zahra, State of Kuwait.
- Alamiri, MD, ABPN, ScD, Consultant Psychiatrist, Chairperson, Al-Manara CAP Centre, KCMH, Kuwait, and Tufts University, Medford, United States.
27 October 2022
Abstract
ASD is commonly associated with a host of challenging behaviours. Pharmacotherapy is indicated if psycho-social and educational interventions fail. Atypical antipsychotics have the strongest evidence-base so far, with both risperidone and aripiprazole are FDA-approved. Unfortunately, their use is fraught with metabolic and neuro-hormonal side effects. Here, authors report on a case of ASD/mild ID with behavioural dyscontrol that failed multiple psychotropic trials and ultimately responded favourably to agomelatine monotherapy. This was achieved with excellent tolerability. This might open new venues in such complicated cases.
Keywords: ASD; agomelatine; behavioral dyscontrol.
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