Combined immunodeficiency in a patient with c-Rel deficiency
Affiliations
Affiliations
- Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
- Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass; Department of Pediatrics, King Saud University, Riyadh, Saudi Arabia.
- Department of Pediatrics, Faculty of Medicine, Kuwait University, and Allergy and Clinical Immunology Unit, Department of Pediatrics, Al-Sabah Hospital, Kuwait City, Kuwait.
- Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass. Electronic address: Janet.Chou@childrens.harvard.edu.
Abstract
This study reports a homozygous mutation in REL abrogating c-Rel protein expression in a patient with combined immunodeficiency characterized by susceptibility to Mycobacterium tuberculosis, Salmonella, Cryptosporidium, and cytomegalovirus.
Conflict of interest statement
Conflict of interest: The authors declare no conflicts of interest.
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