An Atypical Case of Middle East Respiratory Syndrome in a Returning Traveler to Korea from Kuwait, 2018
Affiliations
Affiliations
- 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Abstract
We report a case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in a 61-year-old businessman returning from Kuwait. The patient arrived there on August 16, 2018, developed watery diarrhea on August 28 (day 0), and came back to Korea on September 7 (day 10) as his condition worsened. Upon arrival, he complained of diarrhea and weakness, but denied any respiratory symptoms, and he directly went to visit an emergency room. Chest radiography revealed interstitial infiltrates in the lungs, and he was immediately transferred to an isolation unit. Quantitative real-time PCR analysis of sputum samples taken on day 11 returned positive for MERS-CoV. No secondary MERS-CoV infection was identified among people who had close contact with him. This case underscores the importance of a high index of suspicion of MERS-CoV infection in any febrile patients who present after a trip to the Middle East.
Keywords: Diarrhea; Infection Transmission; Korea; Kuwait; MERS-CoV.
Conflict of interest statement
Disclosure: The authors have no potential conflicts interest to disclose.
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KMEL References
References
-
- Hijawi B, Abdallat M, Sayaydeh A, Alqasrawi S, Haddadin A, Jaarour N, et al. Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation. East Mediterr Health J. 2013;19 Suppl 1:S12–S18. - PubMed
-
- World Health Organization. Middle East respiratory syndrome coronavirus (MERS-CoV) [Updated 2018]. [Accessed Oct 12, 2018]. http://www.who.int/emergencies/mers-cov/en/
-
- Korea Centers for Disease Control and Prevention. Middle East respiratory syndrome statistics (Korean) [Updated 2018]. [Accessed Oct 12, 2018]. http://www.cdc.go.kr/CDC/contents/CdcKrContentView.jsp?cid=140626&menuId....