Incidental brain metastasis of breast cancer detected on 18F-Sodium Fluoride (NaF) PET-CT

Sharjeel Usmani 1, Najeeb Ahmed 2, Samreen Muzaffar 2, Fareeda Al Kandari 3

Affiliations

01 October 2020

Abstract

18F- Sodium Fluoride (NaF) is an excellent bone imaging agent used for skeletal staging but can also be localized in extra osseous calcifying lesions. We report a case of a 38-year-old woman with breast carcinoma referred for 18F-NaF PET-CT to evaluate possible metastatic lesions. 18F-NaF PET-CT detected incidental focal soft tissue tracer uptake in the right cerebellum with no sign of calcification seen on CT images. Subsequent MRI show high intensity signal lesion confirming brain metastasis. Extra osseous 18F-NaF uptake may provide important diagnostic information that might alter patient management.

Keywords: 18F-NaF PET-CT, Breast cancer, PET/MRI, Extra osseous uptake, Metastasis..

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