Former mucinous bronchioloalveolar carcinoma revisited

Mohammed H Alshati 1, Mohammed M Yaktien 2, Kenneth C Katchy 3

Affiliations

01 January 2013

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doi: 10.1155/2013/284323

Abstract

This is a brief case report of invasive multicentric mucinous adenocarcinoma presented at a rather young age with bronchorrhea and persistent consolidation that ended up with the patient demise; nevertheless, we demonstrate relevant radiological and pathological features with emphasis on the new classification of bronchioloalveolar carcinoma, a term that should no longer be in use.

Figures

Figure 1 (a) Plain posteroanterior chest radiograph showing diffuse bilateral mid and lower lung zone consolidation. (b) Axial CT scan (lung window, slice thickness: 2 mm) showing scattered nodules (arrows) combined with multifocal consolidation, ground glass opacities, and septal wall thickening. Centrilobular nodules are also evident in the right lung (between arrow heads) and thought to represent aerogenous spread of tumor cells. (c) Diffuse bilateral multilobar consolidation (black arrows) with the right lower lobe showing a mixture of consolidation, cystic airspaces, and pseudocavitations (white arrows).

Figure 1 (a) Plain posteroanterior chest radiograph showing diffuse bilateral mid and lower lung zone consolidation. (b) Axial CT scan (lung window, slice thickness: 2 mm) showing scattered nodules (arrows) combined with multifocal consolidation, ground glass opacities, and septal wall thickening. Centrilobular nodules are also evident in the right lung (between arrow heads) and thought to represent aerogenous spread of tumor cells. (c) Diffuse bilateral multilobar consolidation (black arrows) with the right lower lobe showing a mixture of consolidation, cystic airspaces, and pseudocavitations (white arrows).

Figure 2 (a) Mucinous adenocarcinoma with lepidic growth pattern (white arrows). Two foci of invasion are seen close to a vessel (black arrow) and around a bronchiole (arrow head). Mucin is present in the alveoli (H&E ×20). (b) The photograph depicts lepidic pattern (black arrows). Invasion of the peribronchiolar tissue is also evident at the center (between white arrows) (H&E ×100).

Figure 2 (a) Mucinous adenocarcinoma with lepidic growth pattern (white arrows). Two foci of invasion are seen close to a vessel (black arrow) and around a bronchiole (arrow head). Mucin is present in the alveoli (H&E ×20). (b) The photograph depicts lepidic pattern (black arrows). Invasion of the peribronchiolar tissue is also evident at the center (between white arrows) (H&E ×100).

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