Complications in paediatric liver transplant from Kuwait when transplanted abroad
Affiliations
Affiliations
- Thuniyan Al-Ghanim, GI Center & University of Kuwait, Kuwait.
Abstract
Background and study aims: Since the introduction of liver transplantation (LTx) in children suffering from liver failure in 1963, many centres around the world have offered this service to children that have no other alternative. The aim of this retrospective study is to analyse the results of paediatric liver transplant in Kuwait over the last decade.
Patients and methods: A retrospective chart review was done involving paediatric patients during the time period of 1995-2004. The information collected included patient demographics, indications for liver transplantation, survival of both patient and allograft, and complications.
Results: A total of 16 cases were found and analysed. The mean age was 3.6years (ranged 5months-17years). There were nine boys and seven girls. The most common indications for LTx were biliary atresia and metabolic liver disease. All the liver transplants were done abroad. There were totally nine deceased donor and seven living related cases. The complications were acute cellular rejection in five, hypertension in two, biliary complications in four, cytomegalovirus (CMV) infection in three and post lymphoproliferative disease in two cases. All but one patient are presently alive.
Conclusion: The above information demonstrates that LTx in Kuwati children is safe and improves the quality of life for those that would otherwise have no other alternative.
Similar articles
Paediatric liver transplantation: Queen Mary Hospital experience.
Chan KL, Fan ST, Saing H, Wei WI, Lo CM, Tsoi NS, Ng IO, Chau MT, Tsoi WK, Chan J, Yuen KY, Tam PK, Wong J.Chin Med J (Engl). 1998 Jul;111(7):610-4.PMID: 11245047
Outcome of liver transplantation for children with liver disease.
Aw MM, Phua KB, Ooi BC, Da Costa M, Loh DL, Mak K, Tan KC, Isaac J, Prabhakaran K, Quak SH.Singapore Med J. 2006 Jul;47(7):595-8.PMID: 16810431
Auckland paediatric liver transplant experience 1990-2000.
Smith J, Wesley A, Chin S, Harding J.N Z Med J. 2002 May 24;115(1154):244-5.PMID: 12117177
A single center experience of combined liver kidney transplantation.
Mehrabi A, Fonouni H, Ayoub E, Rahbari NN, Müller SA, Morath Ch, Seckinger J, Sadeghi M, Golriz M, Esmaeilzadeh M, Hillebrand N, Weitz J, Zeier M, Büchler MW, Schmidt J, Schmied BM.Clin Transplant. 2009 Dec;23 Suppl 21:102-14. doi: 10.1111/j.1399-0012.2009.01146.x.PMID: 19930323 Review.
[Liver transplantation in children].
Valayer J.Presse Med. 1995 Oct 21;24(31):1438-43.PMID: 8545333 Review. French.
References
https://pubmed.ncbi.nlm.nih.gov/