Management of Type 2 diabetes in Ramadan: Low-ratio premix insulin working group practical advice
Affiliations
Affiliations
- BC University Health Board, Glan Clwyd Hospital, Wales.
- Department of Internal Medicine, Etablissement Hospitalo-Universtaire, Oran, Algeria.
- Professor of Diabetes and Internal Medicine, Alexandria University, Alexandria, Egypt.
- Department of Endocrinology, Manipal Hospital, Bangalore, Karnataka, India.
- Department of Endocrinology, GD Diabetes Hospital, Kolkata, West Bengal, India.
- Al-Nour Hospital, Mekkah, Saudi Arabia.
- Dasman Diabetes Institute, Dasman, Kuwait.
- Diabetes Center Benghazi, Benghazi, Libya.
- Department of Endocrinology, University Hospital Ibn Sina - Rabat, Morocco.
- Department of Endocrinology, Chris Hani Baragwaneth Hospital, University of Witwatersrand, Fordsburg, South Africa.
- National Institute of Nutrition, Tunis, Tunisia.
- Department of Endocrinology, SFAX, Tunisia.
- Dubai Hospital, Dubai Health Authority - DHA, Dubai, United Arab Emirates.
- Rashid Centre for Diabetes and Research, Sheikh Khalifa Hospital, Ajman, UAE.
- Internist, EHM, Hoofddorp, Netherlands.
Abstract
The challenge of insulin use during Ramadan could be minimized, if people with diabetes are metabolically stable and are provided with structured education for at least 2-3 months pre-Ramadan. Although, American diabetes association (ADA) recommendations 2010 and South Asian Consensus Guideline 2012 deal with management of diabetes in Ramadan and changes in insulin dosage, no specific guidance on widely prescribed low-ratio premix insulin is currently available. Hence, the working group for insulin therapy in Ramadan, after collective analysis, evaluation, and opinion from clinical practice, have formulated a practical advice to empower physicians with pre-Ramadan preparation, dose adjustment, and treatment algorithm for self-titration of low-ratio premix insulin.
Keywords: Hyperglycemia; hypoglycemia; low-ratio premix insulin; ramadan; type 2 diabetes.
Conflict of interest statement
Conflict of Interest: None declared.
Similar articles
Attitude and safety of patients with diabetes observing the Ramadan fast.
Ba-Essa EM, Hassanein M, Abdulrhman S, Alkhalifa M, Alsafar Z.Diabetes Res Clin Pract. 2019 Jun;152:177-182. doi: 10.1016/j.diabres.2019.03.031. Epub 2019 Apr 1.PMID: 30946851
Consensus on Initiation and Intensification of Premix Insulin in Type 2 Diabetes Management.
Mohan V, Kalra S, Kesavadev J, Singh AK, Kumar A, Unnikrishnan AG, Chawla R, Mukherjee JJ, Sahay RK, Kumar JS, Bhoraskar A, Asirvatham AJ, Panda JK, Zargar AH, Das AK.J Assoc Physicians India. 2017 Apr;65(4):59-73.PMID: 28527166
Bashier AMK, Hussain AKB, Alawadi F, Alsayyah F, Alsaeed M, Rashid F, Abdelgadir E, Bachet F, Abuelkheir S, Elsayed M, Hassanein M.Diabetes Res Clin Pract. 2019 Apr;150:301-307. doi: 10.1016/j.diabres.2019.01.037. Epub 2019 Feb 12.PMID: 30768940
Pathan F, Latif ZA, Sahay RK, Zargar AH, Raza SA, Khan AK, Siddiqui NI, Amin F, Ishtiaq O, Shrestha D, Somasundaram N, Kalra S.J Pak Med Assoc. 2016 Jun;66(6):777-8.PMID: 27339590
Masood SN, Alvi SF, Ahmedani MY, Kiran S, Zeeshan NF, Basit A, Shera AS.Diabetes Metab Syndr. 2014 Oct-Dec;8(4):225-9. doi: 10.1016/j.dsx.2014.09.008. Epub 2014 Oct 22.PMID: 25450821
Cited by
Ibrahim M, Davies MJ, Ahmad E, Annabi FA, Eckel RH, Ba-Essa EM, El Sayed NA, Hess Fischl A, Houeiss P, Iraqi H, Khochtali I, Khunti K, Masood SN, Mimouni-Zerguini S, Shera S, Tuomilehto J, Umpierrez GE.BMJ Open Diabetes Res Care. 2020 May;8(1):e001248. doi: 10.1136/bmjdrc-2020-001248.PMID: 32366501 Free PMC article. Review.
Kalra S, Farooqi MH, El-Houni AE.Indian J Endocrinol Metab. 2015 Sep-Oct;19(5):686-90. doi: 10.4103/2230-8210.163214.PMID: 26425485 Free PMC article.
Recommendations for management of diabetes during Ramadan: update 2015.
Ibrahim M, Abu Al Magd M, Annabi FA, Assaad-Khalil S, Ba-Essa EM, Fahdil I, Karadeniz S, Meriden T, Misha'l AA, Pozzilli P, Shera S, Thomas A, Bahijri S, Tuomilehto J, Yilmaz T, Umpierrez GE.BMJ Open Diabetes Res Care. 2015 Jun 16;3(1):e000108. doi: 10.1136/bmjdrc-2015-000108. eCollection 2015.PMID: 26113983 Free PMC article.
Fasts, feasts and festivals in diabetes-1: Glycemic management during Hindu fasts.
Kalra S, Bajaj S, Gupta Y, Agarwal P, Singh SK, Julka S, Chawla R, Agrawal N.Indian J Endocrinol Metab. 2015 Mar-Apr;19(2):198-203. doi: 10.4103/2230-8210.149314.PMID: 25729681 Free PMC article. Review.
References
-
- Benaji B, Mounib N, Roky R, Aadil N, Houti IE, Moussamih S, et al. Diabetes and Ramadan review of the literature. Diabetes Res Clin Pract. 2006;73:117–25. - PubMed
-
- Salti I, Bénard E, Detournay B, Bianchi-Biscay M, Brigand CL, Voinet C, et al. A population-based study of diabetes and its characteristics during the fasting month of ramadan in 13 countries: Results of the epidemiology of diabetes and ramadan 1422/2001 (EPIDIAR) study. Diabetes Care. 2004;27:2306–11. - PubMed
-
- Bravis V, Hui E, Salih S, Mehar S, Hassanein M, Devendra D. Ramadan education and awareness in diabetes (READ) programme for muslims with type 2 diabetes who fast during Ramadan. Diabet Med. 2010;27:327–31. - PubMed
-
- Hassanein MM. Diabetes and ramadan: How to achieve a safer fast for Muslims with diabetes. Br J Diabetes Vasc Dis. 2010;10:246–50.
-
- Indian National Consensus Group. Premix Insulin: Initiation and continuation guidelines for management of diabetes in primary care. J Assoc Physician India. 2009;57:S42–6.
-
- Soewondo P, Adam JM, Sanusi H, Soeatmadji DW. A multicenter, prospective, non-interventional evaluation of efficacy and safety of using biphasic insulin aspart as monotherapy, or in combination with oral hypoglycaemic agent, in the treatment of type 2 Diabetic Patients Before, During, and After Ramadan. J Indones Med Assoc. 2009;59:574–9.
-
- Mattoo V, Milicevic Z, Malone JK, Schwarzenhofer M, Ekangaki A, Levitt LK, et al. A comparison of insulin lispro Mix 25 and human insulin 30/70 in the treatment of type 2 diabetes during Ramadan. Diabetes Res Clin Pract. 2003;59:137–43. - PubMed
-
- Hui E, Bravis V, Salih S, Hassanein M, Devendra D. Comparison of Humalog Mix 50 with Human insulin Mix 30 in type 2 diabetes patients during Ramadan. Int J Clin Pract. 2010;64:1095–99. - PubMed