Familial manic-depressive illness with deleted short arm of chromosome 21: coincidental or causal?

Affiliations

01 December 1989

-

doi: 10.1192/bjp.155.6.856


Abstract

A 35-year-old Arab lady and her mother, both with bipolar manic-depressive illness and 46,XX,21p-(pcen----pter), are reported. The clinical significance of this association is considered.


Similar articles

Complementary duplication and deletion of 17 (pcen----p11.2): a family with a supernumerary chromosome comprised of an interstitially deleted segment.

Friedman JM, Harrod MJ, Howard-Peebles PN.Am J Med Genet. 1992 Sep 1;44(1):37-40. doi: 10.1002/ajmg.1320440109.PMID: 1519647

Linkage study between manic-depressive illness and chromosome 21.

Ewald H, Eiberg H, Mors O, Flint T, Kruse TA.Am J Med Genet. 1996 Apr 9;67(2):218-24. doi: 10.1002/(SICI)1096-8628(19960409)67:2<218::AID-AJMG15>3.0.CO;2-M.PMID: 8723052

[A case of deletion of the short arm of the chromosome 21 (21p-) (christchurch chromosome) discovered prenatally:clinical and cytogenetic data].

Tavokina LV, Vorsanova SG, Zukin VD, Sopko NI, Zinchenko VM, VeselovskiÄ­ VV, Bychkova AM, Nikitchina TV, Iurov IuB.Tsitol Genet. 2004 Jan-Feb;38(1):26-30.PMID: 15098444 Russian.

Inherited deletion of chromosome (21p-) in a child with congenital malformation and psychomotor retardation.

Kar B, Prabhakara K, Murthy SK.Indian Pediatr. 1992 Jul;29(7):929-34.PMID: 1428153 Review. No abstract available.

Genetics of manic depressive illness.

MacKinnon DF, Jamison KR, DePaulo JR.Annu Rev Neurosci. 1997;20:355-73. doi: 10.1146/annurev.neuro.20.1.355.PMID: 9056718 Review.


Cited by

Chromosomal aberrations and schizophrenia. Autosomes.

Bassett AS.Br J Psychiatry. 1992 Sep;161:323-34. doi: 10.1192/bjp.161.3.323.PMID: 1393302 Free PMC article. Review.


KMEL References