Prevalence of congenital adrenal hyperplasia in Kuwait
Affiliations
Affiliations
- Department of Paediatrics, Farwaniya Hospital, Kuwait.
Abstract
Between 1978 and 1988 congenital adrenal hyperplasia (CAH) was diagnosed in 60 children in Kuwait with an estimated prevalence of 1:9,000 livebirths, which is higher than that reported from Europe and Canada. In addition, there was presumptive evidence of CAH resulting in the death of 20 other children, giving a prevalence figure of 1:7000. There were 41 girls (68%) and 19 boys (32%). Thirty-one of the girls (75.6%) and 11 of the boys (57.9%) were saltlosers. Fifty-four patients (90%) were diagnosed as 21-hydroxylase deficient, 3 patients (5%) had a deficiency of the 3 beta-hydroxy-steroid dehydrogenase enzyme, and 3 patients (5%) showed a deficiency of 11 beta-hydroxylase.
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References
-
- Helv Paediatr Acta. 1958 Nov;13(5):426-31 - PubMed
-
- Arch Dis Child. 1980 Aug;55(8):622-5 - PubMed
-
- Endocrinol Metab Clin North Am. 1988 Jun;17(2):339-66 - PubMed
-
- Arch Dis Child. 1988 Jun;63(6):624-8 - PubMed
-
- Clin Genet. 1985 May;27(5):483-6 - PubMed
-
- Clin Endocrinol Metab. 1982 Mar;11(1):89-125 - PubMed
-
- Arch Dis Child. 1972 Apr;47(252):302-4 - PubMed
-
- Clin Endocrinol (Oxf). 1983 Aug;19(2):259-64 - PubMed
-
- J Pediatr. 1969 Sep;75(3):492-4 - PubMed
-
- Pediatr Clin North Am. 1979 Feb;26(1):77-89 - PubMed
-
- Arch Dis Child. 1988 Jun;63(6):617-23 - PubMed
-
- J Clin Invest. 1956 Feb;35(2):213-22 - PubMed
-
- Helv Paediatr Acta. 1980 Mar;35(1):5-11 - PubMed
-
- Arch Dis Child. 1987 Jul;62(7):659-62 - PubMed