Trends in Childhood Cancer in Kuwait: Data From the 2004-2017 Registry
Affiliations
Affiliations
- Pediatric Hematology and Oncology, National Bank of Kuwait Specialized Hospital for Children, Sabah, KWT.
- Pediatrics, National Bank of Kuwait Specialized Hospital for Children, Sabah, KWT.
- Pediatric Oncology, National Bank of Kuwait Specialized Hospital for Children, Sabah, KWT.
- Pediatric Oncology, Ministry of Health, Kuwait City, KWT.
Abstract
Background and objective There is a lack of updated data regarding pediatric cancer in Kuwait, with no separate childhood cancer registry available in the country prior to this study. We aimed to determine the trends in different cancer types with respect to international statistics, in order to understand their nature and identify gaps in their diagnosis and management. Methods This retrospective study was based on data obtained from the first national childhood cancer registry of the National Bank of Kuwait (NBK) Specialized Hospital for Children, the only hospital that manages pediatric cancer patients in Kuwait. The registry included the data of all children with cancer in Kuwait from 2004 to 2017 and had complete data files. Findings The total number of patients in the childhood cancer registry was 1,387. A total of 1,009 files met our eligibility criteria. In 2017, the incidence of childhood leukemia was determined to be six per 100,000 people, and for other cancers, it was 12.6 per 100,000 people. The most common cancer was leukemia (457 patients), followed by lymphoma (141 patients), and brain tumors (92 patients). The majority of children received chemotherapy (n=891, 88.3%). Post induction or treatment, the majority of patients achieved complete remission (n=790, 78.3%). The overall survival rate of children with cancer was around 80%. Major complications developed in 9% of patients. Conclusion These findings highlight the importance of hospital-based cancer registries. Active data management programs are essential to monitor outcomes, measure the effectiveness of current practice, and improve the quality of care.
Keywords: cancer registry; childhood cancer; leukemia; neoplasm; pediatric oncology.
Conflict of interest statement
The authors have declared that no competing interests exist.
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KMEL References
References
-
- Population estimates in Kuwait by age, nationality and sex. [Feb;2021 ];https://csb.gov.kw/Pages/Statistics_en?ID=67&ParentCatID=1 2020
-
- Kuwait National Development Plan. [Feb;2021 ];Kuwait National Development Plan. https://newkuwaitsummit.com/kndp#:~:text=The%20Kuwait%20National%20Devel... 2019
-
- The importance of registries in cancer control. Leal YA, Fernández-Garrote LM, Mohar-Betancourt A, Meneses-García A. Salud Publica Mex. 2016;58:309–316. - PubMed
-
- Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial. Vora A, Goulden N, Wade R, et al. Lancet Oncol. 2013;14:199–209. - PubMed
-
- The challenge of childhood cancer in developing countries. Haileamlak A. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913186/ Ethiop J Health Sci. 2016;26:199–200. - PMC - PubMed
-
- Towards optimal clinical and epidemiological registration of haematological malignancies: guidelines for recording progressions, transformations and multiple diagnoses. Gavin A, Rous B, Marcos-Gragera R, et al. Eur J Cancer. 2015;51:1109–1122. - PubMed
-
- Racial, ethnic, and age differences in the incidence and survival of childhood cancer in Oklahoma, 1997-2012. Janitz AE, Campbell JE, Pate A, Anderson A, McNall-Knapp R. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119755/ J Okla State Med Assoc. 2016;109:355–365. - PMC - PubMed
-
- Childhood cancer epidemiology in low-income countries. Howard SC, Metzger ML, Wilimas JA, Quintana Y, Pui CH, Robison LL, Ribeiro RC. Cancer. 2008;112:461–472. - PubMed
-
- National Cancer Institute: cancer in children and adolescents. [Feb;2021 ];https://www.cancer.gov/types/childhood-cancers/child-adolescent-cancers-... 2018
-
- Children with Down syndrome and leukemia in Kuwait-experience of the only pediatric hematology oncology department in Kuwait. Bourusly M, Obaid M, Bourhamah M. Cancer Reports Rev. 2017;1:3–4.
-
- Risk of Down syndrome birth: consanguineous marriage is associated with maternal meiosis-II nondisjunction at younger age and without any detectable recombination error. Ray A, Oliver TR, Halder P, Pal U, Sarkar S, Dutta S, Ghosh S. Am J Med Genet A. 2018;176:2342–2349. - PubMed
-
- Risk of cancer among children and young adults with congenital heart disease compared with healthy controls. Mandalenakis Z, Karazisi C, Skoglund K, Rosengren A, Lappas G, Eriksson P, Dellborg M. JAMA Netw Open. 2019;2:0. - PubMed
-
- Efficient use of budget needed to enhance education’s quality, ranking in Kuwait. [Feb;2021 ];https://www.pressreader.com/kuwait/kuwait-times/20170228/281573765474454 Kuwait Times. 2017
-
- Survival from tumours of the central nervous system in Danish children: is survival related to family circumstances? Erdmann F, Winther JF, Dalton SO, et al. Int J Cancer. 2018;142:671–680. - PubMed
-
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. CA Cancer J Clin. 2018;68:394–424. - PubMed
-
- Surviving childhood cancer: a sobering story. Eapen M. Blood. 2018;131:2603–2604. - PubMed
-
- National Cancer Institute: SEER cancer statistics review, 1975-2017. [Nov;2020 ];https://seer.cancer.gov/csr/1975_2017/ 2020
-
- Late effects of childhood cancer and its treatment. Landier W, Armenian S, Bhatia S. Pediatr Clin North Am. 2015;62:275–300. - PubMed