18F-FDG PET Uptake in the Scalp After Platelet-Rich Plasma Therapy
Affiliations
Affiliations
- From the Department of Nuclear Medicine, Kuwait Cancer Control Centre.
- Department of Nuclear Medicine, Jaber Al-Ahmad Al-Sabah Hospital, Kuwait City, Kuwait.
- Jack Brignall PET-CT Centre, Castle Hill Hospital, Cottingham, United Kingdom.
Abstract
18F-FDG PET/CT has been found useful for the detection of the source of infection/inflammation in the body. Platelet-rich plasma is a new treatment modality in which plasma is injected subdermally or intradermally for potential hair regrowth into the scalp. We report a case of 43-year-old woman with right breast cancer who underwent surgery, chemotherapy, and radiotherapy 2 years ago and is currently on hormonal therapy. 18F-FDG PET/CT demonstrate incidental findings of increased FDG avidity in the scalp after platelet-rich plasma therapy.
Conflict of interest statement
Conflicts of interest and sources of funding: none declared.
References
- Gentile P, Garcovich S, Bielli A, et al. The effect of platelet-rich plasma in hair regrowth: a randomized placebo-controlled trial. Stem Cells Transl Med. 2015;4:1317–1323.
- Cervantes J, Perper M, Wong LL, et al. Effectiveness of platelet-rich plasma for androgenetic alopecia: a review of the literature. Skin Appendage Disord. 2018;4:1–11.
- Marx RE. Platelet-rich plasma (PRP): what is PRP and what is not PRP? Implant Dent. 2001;10:225–228.
- Marwah M, Godse K, Patil S, et al. Is there sufficient research data to use platelet-rich plasma in dermatology? Int J Trichology. 2014;6:35–36.
- Kim DH, Je YJ, Kim CD, et al. Can platelet-rich plasma be used for skin rejuvenation? Evaluation of effects of platelet-rich plasma on human dermal fibroblast. Ann Dermatol. 2011;23:424–431.
- Leo MS, Kumar AS, Kirit R, et al. Systematic review of the use of platelet-rich plasma in aesthetic dermatology. J Cosmet Dermatol 2015;14:315–323.
- Boswell SG, Cole BJ, Sundman EA, et al. Platelet-rich plasma: a milieu of bioactive factors. Arthroscopy. 2012;28:429–439.
- Stumpe KD, Dazzi H, Schaffner A, et al. Infection imaging using whole-body FDG-PET. Eur J Nucl Med. 2000;27:822–832.
- Kubota R, Yamada S, Kubota K, et al. Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: high accumulation in macrophages and granulation tissues studied by microautoradiography. J Nucl Med. 1992;33:1972–1980.
- Sánchez-Carpintero I, Candelas D, Ruiz-Rodríguez R. Dermal fillers: types, indications, and complications [in Spanish]. Actas Dermosifiliogr 2010;101:381–393.
- Ginat DT, Schatz CJ. Imaging features of midface injectable fillers and associated complications. AJNR Am J Neuroradiol. 2013;34:1488–1495.